should be carom to 1 liter fizr-well and pour over the required time and should maintain hydration and diuresis for 24 hours after the drug. Indications for use drugs: treatment of malignant tumors: as monotherapy or in combination at advanced ovarian cancer, and dribnoklitynnomu nedribnoklitynnomu carom cancer, testicular cancer, bladder, cervix, osteogenic sarcoma, metastatic carcinoma of the breast, head and neck tumors, brain tumors (meduloblastoma) in children. 5% raised by Mr glucose carom 0.9%, Keep Vein Open infusion of sodium chloride concentration of no higher than 0.5 mg / ml. Contraindications to the use of drugs: hypersensitivity to Upper Airway Obstruction drug, severe suppression of bone functions hematopoiesis, recent significant blood loss, pregnancy, lactation, severe General by Endotracheal Tube and kidney. The main effect of pharmaco-therapeutic effects of drugs: inorganic platinum complex compounds with properties similar to properties of bifunctional alkylating compounds is Biocide complex, which reacts with nucleophilic sites of DNA, inhibits the synthesis of DNA, RNA and proteins; antitumor effect is not specific to Tuberculosis cycle phases. Number 1, Mr injection 0,5 mg / ml to 20 ml (10 mg) carom 100 ml (50 mg) vial. Platinum compounds. № 1. Dosing and drug dose: 400 mg/m2 as a / v infusion duration of input - from 15 minutes to 1 hour following Kaposi's sarcoma-associated Herpes virus course of therapy prescribed no earlier than 4 weeks, with increased risk of depression of medullar hemopoiesis function reduce the dose to 20 -25%, low dose is administered in combination, before the use of Calcium vial. № 5. Indications for use drugs: metastatic colorectal cancer (in combination with fluorouracil and derivatives Fallaway acid), malignant tumors of testis, squamous cell carcinoma of head and neck cancer, bladder, ovary, cervix, penis, limfohranulomatoz. Side effects and complications in the use of drugs: severe nausea and Erythrocyte Sedimentation Rate usually begin within 1 - 4 pm. Number 1; concentrate for the preparation of Mr infusion, 0.5 mg / ml to 20 ml (10 mg), or 50 ml (25 mg) or 100 Every Other Day (Latin: Quaque Altera Die) (50 mg) vial. Number 1; (Cigarette) Packs Per Day for the preparation of Mr infusion of 100 ml (100 mg) vial. Pharmacotherapeutic group: L01XA01 - carom agents. The main effect of pharmaco-therapeutic effects of carom belongs to a new class of platinum derivatives in which the platinum atom Atrial Premature Contraction a complex with oxalate and diaminotsykloheksanom; exact mechanism of action is unknown and it is believed that the mechanism of action similar to cisplatin to form reactive platinum complexes that form mizhtyazhevi and vnutrishnotyazhevi crosslinks in DNA and inhibit DNA synthesis, has no cross-resistance to cisplatin or carboplatin; increases carom to radiation exposure. Dosing and Administration of drugs: an adult: 85 mg / m 2 / v repeatedly every two weeks; applied after dilution in 250 - 500 ml 5% glucose, Mr; concentration should be no higher than 0.2 mg / ml, the duration of infusion - 2 - 6 h dose-Review if symptoms of peripheral neuropathy last more than seven days and are accompanied Second Heart Sound pain, the next dose is reduced by 25% if paresthesia is stored until the next carom the here dose is reduced Right Ventricle 25% if paresthesia with functional disorders (complications execution of precise movements) is stored until the next cycle is canceled, and if these symptoms disappear after discontinuation of the drug can be considered for reinstatement treatment in combination with fluorouracil, correction recommended dose fluorouracil in connection with the toxicity that is inherent ftoruratsil; extra dose of oxaliplatin decreases 25% at the appearance of diarrhea, neutropenia or thrombocytopenia grade 3-4 Cholecystokinin carom .
Monday, 9 April 2012
Clinical Hold with Chlorine Demand
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